How to install mme e
1 Therefore, the CDC recommends reassessing the benefits and risks when prescribing doses above 50 MME/day. Lower doses of opioids corresponded with reduced risk for overdose however, the CDC was unable to find evidence of a specific MME level that conferred no risk of overdose.įurther evaluation of opioid dosing regimens found that doses above 50 MME/day did not ensure improvement in patients’ function or pain, but led to greater incidences of overdose and death. Compared to opioid doses under 20 MME/day, the risk for overdose increased by a factor of 1.9 to 4.6 with doses between 50 and100 MME/day and a factor of 2.0 to 8.9 with doses over 100 MME/day. 1 Their review of clinical trials discovered that when certain MME levels were surpassed, the risk for overdose drastically increased. The Centers for Disease Control and Prevention (CDC) found that higher doses of opioids are associated with an increased risk for motor vehicle accidents, overdose, and opioid use disorder. 1,2 By converting different opioids to a standard value a prescriber is more able to assess a patient’s potential risk for dose-related adverse events. Morphine milligram equivalents (MME) is a unit of measure used to compare opioids of varying potencies.